The Pyston team has built conda packages for Pyston, as well as covered the top 500 most popular packages with a combination of conda-forge and rebuilding binary packages for Pyston. There’s both a Miniconda-style installer as well as a Docker image with Pyston + conda preinstalled. This should make it much easier for folks to try out Pyston. (You can also build a new Pyston environment in your existing conda install.)
For more details, check out the blog post and give it a try: