Navigator unable to install

Hi, I have run in to some issues with Anaconda Navigator. I used it previously successfully, until I installed this: pip install -U --pre spyder

I restarted spyder, which resulted in an error message about PyQt. I then tried to remove spyder and relaunch. Did not work.

I tried to uninstall Anaconda, which cannot run successfully. What am I missing? Any help is appreciated!